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Senior Principal AI/ML Engineer - Research Sovereign AI

Mayo Clinic | Rochester, United States | Posted April 12, 2026

Position Overview

Position Summary

The Senior Principal AI/ML Engineer for AI Representation & EMR Vectorization is the senior technical leader and lead scientist responsible for architecting Mayo Clinic’s unified multimodal EMR representation layer. This role defines and builds the scientific substrate used by foundational models, clinical agents, and research applications. The individual serves as a hands-on expert and player-coach, guiding technical strategy while contributing directly to model development, graph construction, and representation science. Over time, this position will build and lead a specialized team. 

Key Responsibilities

Scientific & Technical Leadership

  • Design and implement Mayo’s multimodal EMR representation AI architecture, including text, imaging, waveform, structured data, temporal sequences, and multi-visit trajectories.
  • Develop graph-based representations and knowledge graphs linking patients, events, attributes, clin...
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