Role

Our research investigates the molecular and cellular pathogenesis underlying neurodegeneration with the eventual goal of developing new therapeutic strategies to combat neurodegenerative diseases affecting millions of people globally. Our previous work identified a dysregulation of the JNK signaling pathway that contributes to aberrant cell response and toxicity, mediated by disease-associated TDP-43 protein expression. To carry this forward, the successful candidate will further characterise the molecular interaction between TDP-43 and JNK signaling, and dissect the involvement of JNK signaling during TDP-43-mediated neurodegeneration.

Skills, Experience & Qualification needed