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Oligonucleotide Scientist II

ICONMA, LLC | United States, United States | Posted June 23, 2026

Position Overview

Our client, a Biotech company, is looking for a Oligonucleotide Scientist II for their South San Francisco, CA location. Responsibilities:

+ The candidate will work in an oligonucleotide therapeutic drug discovery lab and interface across different therapeutic areas, including neuroscience, immunology and oncology, to help build a comprehensive therapeutic discovery strategy.

+ Good understanding and also troubleshooting experience in oligonucleotide synthesis, impurity profiling is a plus.

+ Collaborate with other scientists to maintain common lab equipment such as oligo synthesizers, HPLC and desalting units.

+ Perform literature reviews, propose, and execute nucleic acid chemistry plans, coordinate chemistry and biology data to support oligonucleotide compound progression.

+ Establish methods for scaled-up synthesis of lead molecules and coordinate material delivery for preclinical studies.

+ Maintaining a high level o...

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